一、 內容
1. Introduction and Principles of Toxicology
2. Exposure and Disposition of Toxicants
3. Metabolism of Toxicants
4. Principles of Systemic Toxicologyl Dose-response concepts, receptor theory
5. Chemical Carcinogenesis and Mutagenesis l Active intermediate, DNA adducts, initiation, promotion, progression, Bioassays.
6. Toxicology of Major Systems and Organsl Nervous, renal, and hematopoietic systems; liver and respiratory systems.
7. Toxic Effects of Specific Environmental Agents
8. Principles of Ecotoxicology
9. Physiologically-based Pharmacokinetic Modeling
10. Introduction to Risk Assessment
11. Case Studies of Controlling Toxicants
二、 教科書
Lu, Frank. C., Basic Toxicology, Hemisphere Publishing Corporation, 1991. Amdur, M. O., John Doull, and Curtis D. Klaassen, Casarett and Doull`s Toxicology, McGraw-Hill, 1991.
三、 成績評量方式　　　　平時作業(20%)、期中考試(40%)、期末考試(40%)。
四、 預修課程　　　　無